Get high grade salvia for science

Get high grade salvia for science

Some people literally forgot the path they took, or didn’t know if they owned their bodies anymore. Others felt their internal organs being pulled in directions across all three levels, and through additional dimensions they did not know existed. A few of them can “feel” things by looking at them.

All of these reports come from people smoking an herb from the salvia family called sage Divine sage, commonly referred to as salvia. This plant has been used in religious ceremonies by the Mazatec people of Mexico for centuries. They associate her with the Virgin Mary, and believe that eating sage enables them to speak to her.

Over the past few decades, the plant has also enjoyed popularity in the United States for its psychoactive effects, and there has been a digital deluge of videos of people smoking it on YouTube. Reactions vary, but often include someone getting out of place, laughing too hard, becoming helpless, tripping, or some combination of the above.

Peter Addy, a researcher now at Yale University, decided to conduct the first large study to describe the subjective effects of smoking saliva. While at the Institute for Transpersonal Psychology in Palo Alto, California, Addy asked 30 participants to smoke sage in a comfortable setting, in the lab, while they sat next to him. (A paramedic was standing outside, but was never needed.) Addie sat next to each person while they smoked a pre-made sample of the herb, and after the 10-15 minute ride, she talked to them about their experiences.

The first and most obvious effect is the surprise of elevation. “When you smoke sage, it’s like you flip a switch, everything is natural, and then immediately everything becomes different,” Addy says. He adds that it is also particularly intense and unique: it avoids comparison to any other type of drug.

In contrast to the effects of other psychoactive substances, the sage experience is also difficult to define or simply describe, as many people have very different journeys, he says.

But one common thread that ran through most trips is that sage changes a person’s “perception”—the body’s sense of its physiological conditions. It also seems to alter self-awareness and sense of reality.

“I got completely involved in it and completely lost my orientation to where I was,” one participant said. Nearly 60% reported similar feelings of disorientation, with some forgetting where they were in space. Addie says some people completely forgot they smoked sage and couldn’t remember why they were in the lab in the first place.

Salvia changed the way people looked at their bodies. “I blended into the air around me,” one woman wrote. “I couldn’t tell if you were part of the carpet or part of the chair,” said another man. It also affected people’s sense of what was real.

Nine of the 30 said they had become completely unaware of their surroundings and had an experience completely removed from the “reality” of the laboratory environment. “I didn’t feel like I was in a position to police myself,” one participant wrote. A total of 11 participants “felt other people or beings” during their experiences. “I had the impression that others could hear me and were around me,” one wrote.

A number of participants reported emotional changes: a third said it made them happy, and four people described feeling afraid. Only two people had what Ade described as a “bad trip,” that is, a difficult experience marked by anxiety. But once the effects wore off, things were fine, he says. In both cases, these individuals said the fear arose primarily from the fact that they had no control over the experience. Four others who did not have a hard time also felt helpless in directing the trip, but they “made it” without too much trouble.

“When you smoke sage, you’re going to have an experience whether you want it or not,” Addy says. Most participants said the trip was very strange, but ultimately neutral, and neither particularly good or bad.

Salvia is one of nature’s most powerful hallucinogens, and it has a strange mode of action, acting on kappa opioid receptors, Ade says. These nerve receptors are thought to be involved in interoception, pain sensing, mood, and consciousness. Unlike many hallucinogens, saliva does not appear to affect levels of the neurotransmitter serotonin.

Studies suggest that sage may also have real potential for treating addiction, as it appears to reduce cravings for substances like cocaine in animals. In fact, it works in the brain in the exact opposite way that most opioids do, Addy says.

Addie adds that sage is powerful, but not particularly dangerous if treated carefully; Due to its unique properties, it can teach us new things about the brain. Although this drug remains legal at the federal level, it is currently banned in a number of states, and other states have legislation working to ban its sale. From a scientific point of view, Addy says, this is not a positive trend.

“Banning a substance can reduce its street use, but it can also reduce useful legitimate medical research, which is what we need to do,” he says.